February 9

A Legacy of Balance: How a 16th-Century Visionary Inspires Sassaia’s Winemaking

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Garbagnina Vineyard: Nebbiolo & Dolcetto

At the heart of Sassaia’s philosophy lies a name etched deep into the annals of both science and heritage—Giulio de Alessandrini di Neuenstein. A 16th-century physician, scholar, and thinker, Giulio’s story is as riveting as it is inspiring. Serving as a counselor to the Council of Trent and lending his expertise to emperors, his pursuits centered on harmony—an intricate balance of body, mind, and nature. His belief in interconnectedness was profoundly visionary, a concept that continues to resonate centuries later in the wines of Sassaia.

Careful selection during Hand Harvested

Giulio approached medicine not as isolated problems but as a symbiosis. He advocated for treatments that complemented the body’s natural rhythms, combining knowledge of plants, the sciences, and the human condition. His methods reflected a system ahead of its time—pragmatically holistic, richly nuanced, and rooted in respecting what is already in place. This understanding of natural balance is the cornerstone of Sassaia’s approach to winemaking.

Sassaia winery hand sorting process: Only the best grapes are selected for our wines.

Centuries later, amidst the rolling vineyards of Monleale in Piedmont, this legacy of balance takes form in Sassaia’s approach to winemaking. Inspired by Giulio’s ethos, Sassaia doesn’t simply adopt a minimal intervention philosophy as a lifestyle trend—it anchors it in science and technology, echoing the very principles Giulio cherished.

But what does minimal intervention truly mean for Sassaia? It’s not leaving things to whimsy or chance; rather, it’s using precise scientific knowledge to craft wines of purity and authenticity. Sulfites are kept to a bare minimum, ensuring the wine’s flavor profile—vibrant aromas and complex flavors—remains unmasked. Fermentations are nurtured naturally, but always with a watchful eye and modern tools ready to ensure perfection. The goal? To allow the vibrant personality of the grape to shine while respecting the unique terroir of Piedmont’s mineral-rich soils.

Enrico de Alessandrini in the cellar: Tasting the wine as it evolves.

This philosophy of minimal intervention is not a rejection of intervention itself but an informed choice to act only when necessary—an approach remarkably similar to Giulio’s medicinal practice. Just as he used medicine to guide the body back to harmony, Sassaia uses technology to gently guide its wines towards a perfect equilibrium.

Yet for Sassaia, the story doesn’t end in the vineyard or the bottle. It flows through the generations of the de Alessandrini family, whose reverence for heritage fuels innovative thinking. Current winemaker Enrico de Alessandrini sees himself as both a guardian of his ancestor’s principles and a steward of the future. Under his stewardship, Burgundian elegance meets Italian terroir, American enology and ancient practices blend seamlessly with groundbreaking techniques. The result? Wines of remarkable finesse—vibrant, complex, and alive, offering a distinct sense of place.

Barrel Tasting the elegance of Derthona SASSAIA Style.

Each bottle of Sassaia is a tribute to Giulio’s enduring legacy, a celebration of balance, and an homage to the passage of time. With every sip, you are not merely tasting wine; you’re experiencing a story that’s over 500 years in the making. It’s a story of a man whose vision echoed across centuries and a family that continues to craft harmony—between tradition and progress, science and craft, nature and innovation.

Raise your glass, and toast not just to wine, but to a philosophy—and the profound connections it brings to life.

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Frequently Asked Questions about Giulio de Alessandrini:

What were Giulio de Alessandrini’s most famous works?

Giulio de Alessandrini authored several significant works, including:

  1. De medicina et medico: Considered his most famous work, this book discusses the nature of medicine and the role of the physician.
  2. Salubrium sive de sanitate tuenda: This work prescribes methods for maintaining health and preventing diseases, including recommendations on exercise, rest, diet, cleanliness, and the use of medications.
  3. Paedotrophia sive de puerorum educatione: This book emphasizes the union of mind and body and the importance of early childhood in shaping a child’s character, examining the roles of the mother and nurse.
  4. In Galeni præcipua scripta annotationes … de theriaca quæstio: In this work, Alessandrini opposes the use of theriaca, a compound used for various diseases and as an antidote to poisons.

What were Giulio Alessandrini’s main contributions to medical theory?

Giulio Alessandrini’s main contributions to medical theory include:

  1. Empirical Approach to Medicine: He emphasized the importance of empirical observation and rational analysis in medical practice. He advocated for studying anatomy, physiology, and the properties of herbs and plants to treat diseases based on observed symptoms rather than relying on superstitious or magical practices.
  2. Rejection of Astrological Predictions: Alessandrini argued against the use of astrological predictions in medicine, considering them unreliable and misleading. He believed that medical practice should be based on empirical evidence and rational analysis rather than the positions of celestial bodies.
  3. Integration of Galenic Principles: He studied and translated the works of the Greek physician Galen, adopting Galen’s pre-experimental method of investigation. Alessandrini’s work reinforced the importance of understanding the body’s functions and the nature of diseases through direct observation and study.
  4. Holistic Health Recommendations: In his work Salubrium sive de sanitate tuenda, Alessandrini provided guidelines for maintaining health and preventing diseases. These included recommendations on exercise, rest, diet, cleanliness, and the use of medications.
  5. Pediatric Care and Education: In Paedotrophia sive de puerorum educatione, he emphasized the importance of the early years of life in shaping a child’s character and the role of the mother and nurse in this process. This work contributed to the development of pediatric care and education.
  6. Concept of the Soul’s Faculties: Alessandrini discussed the faculties of the soul and their association with different parts of the body (rational in the brain, irascible in the heart, and concupiscible in the liver). He linked these faculties to the body’s temperaments, influenced by factors such as diet.

These contributions helped shift medical practice towards a more scientific and evidence-based approach, laying the groundwork for modern medicine. 


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